Epigenetics

Epigenetics is meant by the study of heritable changes in gene function without involving the changes in DNA arrangement. It mainly involves the changes in a chromosome which affects gene activity and functions, and also be used to report any heritable phenotypic change which does not derive from a modification of the genome. Epigenetics defined as the study of the epigenotype, which deals with the study of the properties of the pathways and processes that link the genotype and phenotype. A large number of diseases in humans such as cancer, metabolic syndromes and brain disorders have been related with irregularity in epigenetic processes. Process of cellular differentiation is the one of the example of an epigenetic change in eukaryotic biology.

  • DNA damage
  • Covalent modification
  • Structural Inheritance
  • Nucleosome positioning
  • Transgenerational

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